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SCUBE2 anticorps (Center)

Cet anticorps anti-SCUBE2 est un anticorps Lapin Polyclonal détectant SCUBE2 dans WB, IF et EIA. Adapté pour Humain et Rat.
N° du produit ABIN783651

Aperçu rapide pour SCUBE2 anticorps (Center) (ABIN783651)

Antigène

SCUBE2 (Signal Peptide, CUB Domain, EGF-Like 2 (SCUBE2))

Reactivité

  • 20
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Rat

Hôte

  • 20
Lapin

Clonalité

  • 20
Polyclonal

Conjugué

  • 11
  • 3
  • 2
  • 2
  • 1
  • 1
Cet anticorp SCUBE2 est non-conjugé

Application

  • 16
  • 14
  • 11
  • 9
  • 7
  • 3
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • Épitope

    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center

    Réactivité croisée (Details)

    Species reactivity (tested):Human, rat

    Purification

    Affinity chromatography purified via peptide column

    Immunogène

    17 amino acid peptide near the center of human SCUBE2
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS containing 0.02 % sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    -20 °C

    Stockage commentaire

    Store the antibody (in aliquots) at -20 °C.
  • Antigène

    SCUBE2 (Signal Peptide, CUB Domain, EGF-Like 2 (SCUBE2))

    Autre désignation

    SCUBE2

    Sujet

    SCUBE2 is a member of a family of secreted glycoproteins that contain N-terminal EGF-like repeats and C-terminal cysteine-rich motifs and CUB domain and are expressed in embryonic neuroectoderm and vascular epithelium. SCUBE2 is a close homolog to SCUBE1 and can form a heterodimeric complex with SCUBE1. SCUBE2 is thought to participate in the Hedgehog signaling pathway by specifically interacting with Sonic Hedgehog (SHH) and the receptor PTCH1, enhancing the SHH signaling activity in the raft microdomains of the plasma membrane, and may thus play important roles in organ development and tumor progression.Synonyms: CEGP1, Signal peptide CUB and EGF-like domain-containing protein 2

    ID gène

    57758

    NCBI Accession

    NP_001164161

    UniProt

    Q9NQ36
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