Secernin 1 anticorps (C-Term)

N° du produit ABIN783653

L’anticorps anti-Secernin 1 Polyclonal Lapin est utilisé pour la détection de Secernin 1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IF et EIA.

Aperçu rapide pour Secernin 1 anticorps (C-Term) (ABIN783653)

Antigène: Secernin 1 (SCRN1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Secernin 1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-Secernin 1 anticorps

Épitope: C-Term

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Immunogène: 20 amino acid peptide near the carboxy terminus of human SCRN1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur Secernin 1

Antigène: Secernin 1 (SCRN1)

Autre désignation: Secernin-1 (SCRN1)

Sujet: SCRN1 was first identified as a cytosolic protein that is involved in the regulation of exocytosis from peritoneal mast cells. More recent studies have shown that SCRN1 expression is upregulated in gastric cancer cell lines and may possess epitopes that could function as tumor-associated antigens, potentially providing targets for cancer vaccines in the treatment of gastric cancers. Another report indicates that decreased expression of SCRN1 via RNAi expression resulted in significantly lower rates of cell growth in colorectal cancer cell lines, and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN1 may also be involved in the regulation of cell growth and might be useful as a prognostic tool.Synonyms: KIAA0193

ID gène: 9805

NCBI Accession: NP_001138985

UniProt: Q12765