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CRISP2 anticorps (N-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement CRISP2 dans WB et EIA. Il présente une réactivité envers Humain.
N° du produit ABIN783679

Aperçu rapide pour CRISP2 anticorps (N-Term) (ABIN783679)

Antigène

Voir toutes CRISP2 Anticorps
CRISP2 (Cysteine-Rich Secretory Protein 2 (CRISP2))

Reactivité

  • 14
  • 4
  • 3
Humain

Hôte

  • 11
  • 3
  • 2
Lapin

Clonalité

  • 14
  • 2
Polyclonal

Conjugué

  • 16
Cet anticorp CRISP2 est non-conjugé

Application

  • 15
  • 12
  • 10
  • 4
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Épitope

    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term

    Specificité

    This antibody detects CRISP2 at N-term.

    Réactivité croisée (Details)

    Species reactivity (tested):Human

    Purification

    Affinity chromatography purified via peptide column

    Immunogène

    15 amino acid peptide near the amino terminus of human CRISP2
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Buffer

    PBS containing 0.02 % sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Antigène

    CRISP2 (Cysteine-Rich Secretory Protein 2 (CRISP2))

    Autre désignation

    CRISP2

    Sujet

    The cysteine-rich secretory proteins (CRISP) family is a group of four proteins that are strongly expressed in the male reproductive tract and have been implicated in having roles in male fertility. CRISP2, also known as TPX1, has been implicated in the adhesion between spermatids and Sertoli cells, and with CRISP1, is thought to be involved in sperm-egg fusion. CRISP2 has been shown to regulate the Ca2+ influx through ryanodine receptors (RYR) and may influence the acrosome reaction or sperm motility. CRISP2 has also been shown to bind to the mitogen-activated protein kinase kinase kinase 11 (MAP3K11) and localizes to the developing acrosome, suggesting this CRISP2-MAP3K11 complex may have a role in acrosome development.Synonyms: CRISP-2, CT36, Cancer/testis antigen 36, Cysteine-rich secretory protein 2, GAPDL5, TPX1, Testis-specific protein TPX-1

    ID gène

    7180

    NCBI Accession

    NP_001135879

    UniProt

    P16562
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