KPNA3 anticorps (C-Term)

N° du produit ABIN783735

Détail du produit anti-KPNA3 anticorps

Antigène: KPNA3 (Karyopherin alpha 3 (Importin alpha 4) (KPNA3))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KPNA3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects KPNA3 / Importin alpha-3 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 14 amino acid peptide near the carboxy end of human KPNA3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur KPNA3

Antigène: KPNA3 (Karyopherin alpha 3 (Importin alpha 4) (KPNA3))

Autre désignation: KPNA3 / Importin alpha-3 (KPNA3 Produits)

Synonymes: anticorps IPOA4, anticorps si:dz79f24.2, anticorps importin, anticorps SRP1, anticorps SRP1gamma, anticorps SRP4, anticorps hSRP1, anticorps ipoa4, anticorps srp1, anticorps srp1gamma, anticorps srp4, anticorps karyopherin (importin) alpha 3, anticorps karyopherin alpha 3 (importin alpha 4), anticorps karyopherin subunit alpha 3, anticorps karyopherin alpha 3 (importin alpha 4) L homeolog, anticorps Kpna3, anticorps kpna3, anticorps KPNA3, anticorps kpna3.L

Sujet: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA3, the alpha subunit 3 of karyopherin, is silimar to human KPNA2, suggesting that KPNA3 may be involved in the nuclear transport system. It is ubiquitously expressed and recent studies have shown that human KPNA3 may be associated with schizophrenia.Synonyms: Importin alpha Q2, Karyopherin subunit alpha-3, QIP2, SRP1-gamma

ID gène: 3839

NCBI Accession: NP_002258

UniProt: O00505

Pathways: Protein targeting to Nucleus