TRIP6 anticorps (Center)
Aperçu rapide pour TRIP6 anticorps (Center) (ABIN783745)
Antigène
Voir toutes TRIP6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Specificité
- This antibody detects TRIP6 / OIP1 at Center.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 15 amino acid peptide near the center of human TRIP6
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))
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Autre désignation
- TRIP6 / OIP1
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Sujet
- TRIP6 (Thyroid receptor interacting protein 6) is a zyxin-related focal adhesion molecule involved in cell motility and antiapoptotic responses. TRIP6 is predominantly expressed in kidney, liver and lung. It has three LIM domains, a PDZ-binding motif, a Crk SH2-binding motif and/or other protein interacting domains. TRIP6 regulates NF-kB activation and interacts with RICK and TRAF2, proteins that are involved in TNF signaling. TRIP6 antagonizes Fas-induced apoptosis and promotes Fas-mediated cell migration in apoptosis-resistant glioma cells via Src-dependent phosphorylation of TRIP6 at Tyr-55.Synonyms: OIP-1, OPA-interacting protein 1, TRIP-6, ZRP-1, Zyxin-related protein 1
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ID gène
- 7205
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NCBI Accession
- NP_003293
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UniProt
- Q15654
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Pathways
- Cell-Cell Junction Organization
Antigène
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