PLAC1 anticorps (C-Term)

N° du produit ABIN783753

Cet anticorps anti-PLAC1 Polyclonal Lapin (ABIN783753) détecte spécifiquement PLAC1 dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PLAC1 anticorps (C-Term) (ABIN783753)

Antigène: PLAC1 (Placenta-Specific 1 (PLAC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLAC1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-PLAC1 anticorps

Épitope: C-Term

Specificité: This antibody detects PLAC1 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid peptide near the carboxy terminus of human PLAC1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur PLAC1

Antigène: PLAC1 (Placenta-Specific 1 (PLAC1))

Autre désignation: PLAC1

Sujet: PLAC1 was initially identified as a protein expressed specifically in the placenta and other cells derived from the trophoblast lineage during embryonic development, but has also been found to be expressed ectopically in a wide range of human malignancies, particularly breast cancers. PLAC1 is a membrane-associated protein that is thought to serve a receptor-like function modulating cell-cell or ligand receptor interactions unique to the maternal-placental interface. Decreased expression of PLAC1 is associated with decreased expression of cyclin D1 and reduced expression of AKT kinase, which, combined with the fact that PLAC1 is expressed on the surface of cancer cells, suggests that PLAC1 may be an effective candidate for immunotherapeutic treatments of cancer.Synonyms: Placenta-specific protein 1

ID gène: 10761

NCBI Accession: NP_068568

UniProt: Q9HBJ0