PAPPA2 anticorps (N-Term)
Aperçu rapide pour PAPPA2 anticorps (N-Term) (ABIN783757)
Antigène
Voir toutes PAPPA2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody detects Pappalysin-2 / PAPPA2 at N-term.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 15 amino acid peptide near the amino terminus of human PLAC3
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- PAPPA2 (Pappalysin 2 (PAPPA2))
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Autre désignation
- Pappalysin-2 / PAPPA2
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Sujet
- PLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregnancy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.Synonyms: PAPP-A2, PAPP-E, PLAC3, Pregnancy-associated plasma protein A2, Pregnancy-associated plasma protein E1
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ID gène
- 60676
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NCBI Accession
- NP_064714
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UniProt
- Q9BXP8
Antigène
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