PAPPA2 anticorps (N-Term)

N° du produit ABIN783757

Détail du produit anti-PAPPA2 anticorps

Antigène: PAPPA2 (Pappalysin 2 (PAPPA2))

Épitope: N-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAPPA2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Pappalysin-2 / PAPPA2 at N-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid peptide near the amino terminus of human PLAC3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur PAPPA2

Antigène: PAPPA2 (Pappalysin 2 (PAPPA2))

Autre désignation: Pappalysin-2 / PAPPA2 (PAPPA2 Produits)

Synonymes: anticorps PAPP-A2, anticorps PLAC3, anticorps Pappe, anticorps PAPP-E, anticorps PAPPE, anticorps si:dkey-39f8.1, anticorps pappalysin 2, anticorps Pappa2, anticorps PAPPA2, anticorps pappa2

Sujet: PLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregnancy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.Synonyms: PAPP-A2, PAPP-E, PLAC3, Pregnancy-associated plasma protein A2, Pregnancy-associated plasma protein E1

ID gène: 60676

NCBI Accession: NP_064714

UniProt: Q9BXP8