MFSD2B anticorps (Center)
Aperçu rapide pour MFSD2B anticorps (Center) (ABIN783765)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Specificité
- This antibody detects MFSD2B at Center.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, rat
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 15 amino acid peptide near the center of human MFSD2B
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- MFSD2B (Major Facilitator Superfamily Domain Containing 2B (MFSD2B))
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Autre désignation
- MFSD2B
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Sujet
- Multidrug transporters, such as MFSD2B, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2B is closely related to MFSD2A, which is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting, playing a major role in the induction of MFSD2A expression during adaptive thermogenesis. Unlike MFSD2A, MFSD2B is expressed in few tissues and at relatively low levels, and is not induced during fasting, suggesting that MFSD2B may play other roles.
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ID gène
- 388931
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NCBI Accession
- NP_001073942
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UniProt
- A6NFX1
Antigène
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