PEAR1 anticorps (C-Term)

N° du produit ABIN783779

Détail du produit anti-PEAR1 anticorps

Antigène: PEAR1 (Platelet Endothelial Aggregation Receptor 1 (PEAR1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PEAR1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects PEAR1 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid peptide near the carboxy terminus of human PEAR1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur PEAR1

Antigène: PEAR1 (Platelet Endothelial Aggregation Receptor 1 (PEAR1))

Autre désignation: PEAR1 (PEAR1 Produits)

Synonymes: anticorps MEGF12, anticorps JEDI, anticorps 3110045G13Rik, anticorps Jedi-1, anticorps Megf12, anticorps RGD1305653, anticorps platelet endothelial aggregation receptor 1, anticorps PEAR1, anticorps pear1, anticorps Pear1

Sujet: Platelet endothelial aggregation receptor 1 (PEAR1) is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation. Upon platelet aggregation stimulated by physiological agonists, PEAR1 becomes tyrosine- and serine-phosphorylated, the tyrosine phosphorylation can be inhibited by eptifibatide, an aIIbb3 antagonist that also inhibits platelet aggregation. Recent studies have indicated that genetic variations in PEAR1, may be associated with enhanced agonist-induced platelet aggregation.Synonyms: MEGF12, Multiple EGF-like domains protein 12, Multiple epidermal growth factor-like domains protein 12, Platelet endothelial aggregation receptor 1

ID gène: 375033

NCBI Accession: NP_001073940

UniProt: Q5VY43