EFCAB4A anticorps (Center)

N° du produit ABIN783783

Détail du produit anti-EFCAB4A anticorps

Antigène: EFCAB4A (EF-Hand Calcium Binding Domain 4A (EFCAB4A))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EFCAB4A est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects EFCAB4A at Center.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid peptide near the center of human EFCAB4A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur EFCAB4A

Antigène: EFCAB4A (EF-Hand Calcium Binding Domain 4A (EFCAB4A))

Autre désignation: EFCAB4A (EFCAB4A Produits)

Synonymes: anticorps CRACR2B, anticorps 6330520A15Rik, anticorps BC026645, anticorps Cracr2a, anticorps Efcab4, anticorps RGD1560911, anticorps zgc:158448, anticorps calcium release activated channel regulator 2B, anticorps cracr2b, anticorps CRACR2B, anticorps Cracr2b

Sujet: EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.Synonyms: EF-hand calcium-binding domain-containing protein 4A

ID gène: 283229

NCBI Accession: NP_775855

UniProt: Q8N4Y2