TMEM59 anticorps (N-Term)

N° du produit ABIN783793

Détail du produit anti-TMEM59 anticorps

Antigène: TMEM59 (Transmembrane Protein 59 (TMEM59))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM59 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects TMEM59 at N-term.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid peptide near amino terminus of human TMEM59

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur TMEM59

Antigène: TMEM59 (Transmembrane Protein 59 (TMEM59))

Autre désignation: TMEM59 (TMEM59 Produits)

Synonymes: anticorps Tmem59, anticorps C1orf8, anticorps HSPC001, anticorps 1110001M20Rik, anticorps 3110046P06Rik, anticorps AI256529, anticorps D4Ertd20e, anticorps MTDCF1, anticorps ORF18, anticorps transmembrane protein 59, anticorps tmem59, anticorps Tmem59, anticorps TMEM59

Sujet: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.Synonyms: C1orf8, HSPC001, Liver membrane-bound protein, Transmembrane protein 59

ID gène: 9528

NCBI Accession: NP_004863

UniProt: Q9BXS4