Transmembrane Protein 18 (TMM18) (C-Term) anticorps

N° du produit ABIN783829

Détail du produit

Antigène: Transmembrane Protein 18 (TMM18)

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to Transmembrane protein 18.

Purification: Affinity chromatography

Immunogène: 15 amino acid peptide near the carboxy terminus of human TMEM18.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détail du antigène

Antigène: Transmembrane Protein 18 (TMM18)

Autre désignation: TMEM18 (TMM18 Produits)

Synonymes: anticorps BC024093, anticorps transmembrane protein 18, anticorps transmembrane protein 18 L homeolog, anticorps TMEM18, anticorps Tmem18, anticorps tmem18.L

Sujet: Recent studies have examined how overexpression of certain genes enhances the tropism of neural stem cells (NSCs) for gliomas. Overexpression of Transmembrane protein 18 (TMEM18) provides NSCs and neural precursors an increased migration capacity towards glioblastoma cells in vitro and in the rat brain, while functional inactivation of the gene resulted in an almost complete loss of migration activity, suggesting that TMEM18 could be a potential target in NSC-based glioma therapy. Other recent results suggest that among others, the TMEM18 loci is associated with higher than normal body mass index (BMI) and obesity, indicating there may be a CNS-related role in predisposition to obesity. Multiple isoforms of TMEM18 are known to exist.Synonyms: Transmembrane protein 18

ID gène: 129787

NCBI Accession: NP_690047

UniProt: Q96B42