GFAP anticorps

N° du produit ABIN783875

L’anticorps Lapin Polyclonal anti-GFAP a été validé pour IHC (p). Il convient pour détecter GFAP dans des échantillons de Humain, Rat, Souris, Boeuf (Vache), Poulet, Cobaye, Mouton, Singe et Hamster.

Aperçu rapide pour GFAP anticorps (ABIN783875)

Antigène: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Poulet, Cobaye, Mouton, Singe, Hamster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GFAP est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GFAP anticorps

Specificité: This antibody recognizes Glial Fibrillary Acidic Protein (GFAP). Cellular localization: Cytoplasmic.

Réactivité croisée (Details): Species reactivity (expected):Human, Mouse, Rat, Sheep, Monkey, Hamster, Guinea pig and Chicken.
Species reactivity (tested):Bovine.

Purification: Purified

Immunogène: GFAP isolated from cow spinal cord. Genename: GFAP

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM PBS, pH 7.4, 0.09 % Sodium Azide, 0.2 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur GFAP

Antigène: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Autre désignation: GFAP

Sujet: Glial fibrillary acidic protein (GFAP) is an intermediate-filament (IF) protein that is highly specific for cells of astroglial lineage, although its tissue-specific role is speculative. GFAP has been located in rat kidney glomeruli and peritubular fibroblasts, leydig cells of testis, skin keratinocytes, osteocytes of bones, chondrocytes of epiglottis, bronchus, and stellate-shaped cells of the pancreas and liver. Its expression is essential for normal white matter architecture and blood-brain barrier integrity, and its absence leads to late-onset CNS dysmyelination. GFAP has also been shown to play a role in mitosis by adjusting the filament network present in the cell. During mitosis, there is an increase in the amount of phosphorylated GFAP, and a movement of this modified protein to the cleavage furrow.Synonyms: Glial Fibrillary Acidic Protein

ID gène: 2670

NCBI Accession: NP_001124491