Fascin 2 anticorps (Internal Region)

N° du produit ABIN783923

Détail du produit anti-Fascin 2 anticorps

Antigène: Fascin 2 (FSCN2)

Épitope: Internal Region

Reactivité: Humain, Souris, Rat, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Fascin 2 est non-conjugé

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Séquence: CHHRGSNQLD TNR

Specificité: This antibody is expected to recognize both reported isoforms (NP_001070650.1 and NP_036550.1).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Dog.
Species reactivity (tested):Human.

Purification: Affinity Chromatgraphy

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_001070650.1, NP_036550.1. Genename: FSCN2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Fascin 2

Antigène: Fascin 2 (FSCN2)

Autre désignation: Fascin-2 (FSCN2 Produits)

Synonymes: anticorps fascin-2, anticorps A930022G03, anticorps C630046B20Rik, anticorps ahl8, anticorps RFSN, anticorps RP30, anticorps fascin actin-bundling protein 2, retinal, anticorps fascin actin-bundling protein 1, anticorps fascin actin-bundling protein 2, anticorps FSCN2, anticorps FSCN1, anticorps Fscn2

Sujet: Fascin-2 Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis. Defects in FSCN2 are the cause of retinitis pigmentosa type 30 (RP30) [MIM:607921]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP30 inheritance is autosomal dominant.Synonyms: FSCN2, Retinal fascin

ID gène: 25794

NCBI Accession: NP_001070650