SMC2 anticorps (C-Term)

N° du produit ABIN783969

Cet anticorps anti-SMC2 Polyclonal Chèvre (ABIN783969) détecte spécifiquement SMC2 dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour SMC2 anticorps (C-Term) (ABIN783969)

Antigène: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp SMC2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-SMC2 anticorps

Épitope: C-Term

Séquence: C-SKAKPPKGAH VEV Remarks: Reported variants NP_006435.2, NP_001036015.1 and NP_001036016.1 represent identical protein

Specificité: Recognizes SMC2/CAPE.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence from the C Terminus of the protein sequence according to NP_006435.2. Genename: SMC2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SMC2

Antigène: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Autre désignation: SMC2 / CAPE

Sujet: CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behaviour of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in human cells.Synonyms: CAP-E, Chromosome-associated protein E, SMC protein 2, SMC-2, SMC2L1, Structural maintenance of chromosomes protein 2, XCAP-E homolog

ID gène: 216

NCBI Accession: NP_006435