DBF4 anticorps (Internal Region)

N° du produit ABIN783975

Cet anticorps anti-DBF4 Polyclonal Chèvre (ABIN783975) détecte spécifiquement DBF4 dans WB et EIA. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour DBF4 anticorps (Internal Region) (ABIN783975)

Antigène: DBF4 (DBF4 Homolog (DBF4))

Reactivité: Souris, Rat

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp DBF4 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-DBF4 anticorps

Épitope: Internal Region

Séquence: C-DKKRTEYLPA HEDRT

Specificité: This antibody is expected to recognize both reported isoforms (NP_038754.1 and NP_001177646.1).

Réactivité croisée (Details): Species reactivity (expected):Rat.
Species reactivity (tested):Mouse.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_038754.1, NP_001177646.1.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur DBF4

Antigène: DBF4 (DBF4 Homolog (DBF4))

Autre désignation: DBF4 / ASK

Sujet: DBF4 plays a role as a regulatory subunit for CDC7 which activates its kinase activity. Is required for entry into S phase of the cell cycle. The complex CDC7-DBF4 selectively phosphorylates MCM2 subunit of chromatin-associated MCM complex and then is involved in regulating the initiation of DNA replication during cell cycle.Synonyms: Activator of S phase kinase, Chiffon homolog A, DBF4-type zinc finger-containing protein 1, DBF4A, Protein DBF4 homolog A, ZDBF1

ID gène: 216

NCBI Accession: NP_001177646

Pathways: Mitotic G1-G1/S Phases, DNA Replication