CD51 anticorps (C-Term)

N° du produit ABIN784042

Cet anticorps Lapin Polyclonal détecte spécifiquement CD51 dans WB, IF, IHC (p) et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour CD51 anticorps (C-Term) (ABIN784042)

Antigène: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD51 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-CD51 anticorps

Épitope: C-Term

Specificité: This antibody reacts to ITGAV / CD51.

Purification: Immunoaffinity chromatography

Immunogène: ITGAV antibody was raised against synthetic peptide

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur CD51

Antigène: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Autre désignation: CD51 / ITGAV

Sujet: ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8, 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands, the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction.Synonyms: Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha

ID gène: 3685

NCBI Accession: NP_001138472

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex