DAPP1 anticorps (Internal Region)

N° du produit ABIN784511

Détail du produit anti-DAPP1 anticorps

Antigène: DAPP1 (Dual Adaptor of Phosphotyrosine and 3-phosphoinositides (DAPP1))

Épitope: Internal Region

Reactivité: Humain, Chien, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp DAPP1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes DAPP1.

Réactivité croisée (Details): Species reactivity (expected):Canine and Bovine.
Species reactivity (tested):Human.

Purification: Affinity Chromatography

Immunogène: Peptide with sequence C-KLSQIRKQLNQGE, from the internal region (near C Terminus) of the protein sequence according to NP_055210.2.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur DAPP1

Antigène: DAPP1 (Dual Adaptor of Phosphotyrosine and 3-phosphoinositides (DAPP1))

Autre désignation: DAPP1 (DAPP1 Produits)

Synonymes: anticorps BAM32, anticorps DAPP1, anticorps zgc:111998, anticorps bam32, anticorps Bam32, anticorps dual adaptor of phosphotyrosine and 3-phosphoinositides 1, anticorps dual adaptor of phosphotyrosine and 3-phosphoinositides, anticorps dual adaptor for phosphotyrosine and 3-phosphoinositides 1, anticorps DAPP1, anticorps Dapp1, anticorps dapp1

Sujet: B cell adapter molecule (BAM32) is also designated a dual adapter for phosphotyrosine and 3-phosphotyrosine, and 3-phosphoinositide (DAPP1) or B lymphocyte adapter protein. BAM32 is a B cell-associated adapter that is crucial for B cell antigen receptor signaling regulation. BAM32 interacts with Ptdlns and PLC γ2 and, upon B cell activation, the protein is phosphorylated on tyrosine residues. It is a mainly cytoplasmic protein that can translocate to the cell membrane after cell stimulation. BAM32, which contains one PH domain and one SH2 domain, is primarily expressed in placenta and lung tissues, but can also be detected in heart, liver, pancreas and brain.Synonyms: BAM32, DKFZp667E0716, Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide, HSPC066, hDAPP1

ID gène: 27071

NCBI Accession: NP_055210

Pathways: BCR Signaling