CD163 anticorps (PE)

N° du produit ABIN784617

Cet anticorps anti-CD163 est un anticorps Souris Monoclonal détectant CD163 dans FACS. Adapté pour Humain.

Aperçu rapide pour CD163 anticorps (PE) (ABIN784617)

Antigène: CD163

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD163 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: 5C6-FAT

Détail du produit anti-CD163 anticorps (PE)

Specificité: Monoclonal antibody 5C6 FAT recognizes a membrane glycoprotein on human monocytes and macrophages which is expressed in intermediate and late inflammatory stages. The red R-Phycoerythrin label is particularly useful to avoid the greenish autofluorescence of some cells in their resting state.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Affinity chromatography

Immunogène: Human CD163

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: Phosphate buffered saline pH 7.2 (PBS), 0.09 % Sodium Azide, 10 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.

Date de péremption: 6 months

Détails sur CD163

Antigène: CD163

Autre désignation: CD163

Sujet: CD163 is a scavenger receptor for the haemoglobin-haptoglobin complex, and is upregulated by glucocorticoids and IL-10. The extracellular portion of the receptor is regularly shed and can be found in the circulation. An important function of CD163 seems to be in the adhesion of monocytes to activated endothelial cells. CD163-positive cells include skin histiocytes, Kupffer cells, spleen macrophages of the red pulp, and some thymus macrophages. The antigen is also found abundantly in human term placenta, and regularly in acute and chronic inflammatory lesions. The red R-Phycoerythrin label is particularly useful to avoid the greenish autofluorescence of some cells in their resting state.Synonyms: Hemoglobin scavenger receptor, M130, Macrophage marker, Scavenger receptor cysteine-rich type 1 protein M130

ID gène: 9332

NCBI Accession: NP_004235

UniProt: Q86VB7