GABBR1 anticorps (pSer923) (HRP)

N° du produit ABIN800892

Cet anticorps anti-GABBR1 est un anticorps Lapin Polyclonal détectant GABBR1 dans WB, ELISA, IHC (p) et IHC (fro). Adapté pour Humain, Rat et Souris.

Aperçu rapide pour GABBR1 anticorps (pSer923) (HRP) (ABIN800892)

Antigène: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GABBR1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-GABBR1 anticorps (HRP)

Épitope: pSer923

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from mouse GABBR1 around the phosphorylation site of Ser923

Isotype: IgG

Information d'application

Indications d'application: WB 1:100-1000
IHC-P 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Gentamicin sulfate

Précaution d'utilisation: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GABBR1

Antigène: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Autre désignation: Gabbr1

Sujet:

Synonyms: GABBR1 phospho S1180, GABBR1 phospho Ser1180, p-GABBR1 Ser1180, GABAb Receptor 1, dJ271M21.1.1, dJ271M21.1.2, FLJ92613, GAB B R1, GABA B R1, GABAB R1, GABAB subunit 1c, GABAB1e, GABABR 1, GABABR1, GABB R1, GABBR 1, GABBR1 3, GABBR1, Gamma aminobutyric acid GABA B receptor 1, Gamma aminobutyric acid B receptor 1, Gamma aminobutyric acid type B receptor subunit 1, Gb 1, Gb1, GPRC 3A, GPRC3A, hGB1a, GABR1_HUMAN, Gamma-aminobutyric acid type B receptor subunit 1, GABA B Receptor 1, GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1, Seven transmembrane helix receptor.

Background: Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jun 2009].

ID gène: 54393

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process