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DUX4 anticorps (C-Term)

DUX4 Reactivité: Humain WB, IHC, IF, ICC Hôte: Souris Monoclonal P2B1 unconjugated
N° du produit ABIN863109
  • Antigène Voir toutes DUX4 Anticorps
    DUX4 (Double Homeobox 4 (DUX4))
    Épitope
    • 26
    • 15
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 78
    • 8
    • 8
    • 1
    • 1
    Humain
    Hôte
    • 60
    • 18
    Souris
    Clonalité
    • 60
    • 16
    Monoclonal
    Conjugué
    • 18
    • 8
    • 8
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DUX4 est non-conjugé
    Application
    • 66
    • 32
    • 19
    • 16
    • 13
    • 13
    • 11
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Detects ~45 kDa. No cross-reactivity with DUX4c.
     Réactivité croisée
    Humain, Souris
    Purification
    Protein G Purified
    Immunogène
    C-terminal 76 amino acids of DUX4 with glutathione-s-transferase (gst) tag
    Clone
    P2B1
    Isotype
    IgG1
    Top Product
    Discover our top product DUX4 Anticorps primaire
  • Indications d'application
    • WB (1:1000)
    • ICC/IF (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    1 μg/ml of ABIN863109 was sufficient for detection of DUX4 in 20 μg of HeLa cell lysate by ECL immunoblot analysis using goat anti-mouse IgG: HRP as teh secondary.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C
  • Antigène
    DUX4 (Double Homeobox 4 (DUX4))
    Autre désignation
    DUX4 (DUX4 Produits)
    Synonymes
    anticorps DUX4, anticorps DUX4L, anticorps double homeobox, 4, anticorps double homeobox 4, anticorps DUX4
    Sujet
    DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1 (1). Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function (2-4). In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues (5).
    ID gène
    22947
    NCBI Accession
    NP_149418
    UniProt
    F5GZ66
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