PSIP1 anticorps

N° du produit ABIN865479

Cet anticorps anti-PSIP1 Monoclonal Souris (Clone 6E4) (ABIN865479) détecte spécifiquement PSIP1 dans WB, IHC, IF et ELISA. L’anticorps est réactif avec des échantillons de Humain, Rat et Singe.

Aperçu rapide pour PSIP1 anticorps (ABIN865479)

Antigène: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Reactivité: Humain, Rat, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PSIP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Clone: 6E4

Détail du produit anti-PSIP1 anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CARM1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: WB: 1/500 - 1/2000, IHC:1/200-1/1000, IF: 1/200-1/1000, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100g/100l

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur PSIP1

Antigène: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Autre désignation: PSIP1

Sujet: Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. Tissue specificity: Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions. Synonyms: p52, p75, PAIP, DFS70, LEDGF, PSIP2, MGC74712, PSIP1

Poids moléculaire: 75kDa

ID gène: 11168

Pathways: Chromatin Binding, Ribonucleoprotein Complex Subunit Organization