CTCF anticorps

N° du produit ABIN865482

Cet anticorps anti-CTCF Monoclonal Souris (Clone 1D11) (ABIN865482) détecte spécifiquement CTCF dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Singe.

Aperçu rapide pour CTCF anticorps (ABIN865482)

Antigène: CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CTCF est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 1D11

Détail du produit anti-CTCF anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CTCF expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: WB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100g/100l

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur CTCF

Antigène: CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

Autre désignation: CTCF

Sujet: This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Tissue specificity: Ubiquitous. Absent in primary spermatocytes. Synonyms: CTCF

Poids moléculaire: 83kDa

ID gène: 10664