Complement C4d anticorps (Internal Region)
Aperçu rapide pour Complement C4d anticorps (Internal Region) (ABIN870587)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- Internal Region
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Fonction
- Anti-C4d complement
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Specificité
- C4d complement
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Immunogène
- Peptide derived from internal sequence of human C4.
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Isotype
- IgG
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Indications d'application
- 1:100 - 200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 20 mM Tris-HCI, pH 8.0, Stabilizer: 20 mg/mL BSA, Preservative: 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- +2 °C to +8 °C
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- Complement C4d (C4d) (Complement Component C4d (C4d))
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Autre désignation
- C4d complement
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Sujet
- C4d is a split product of the complement C4 and its deposition serves as a sensitive and specific marker for antibody mediated rejection (AMR) of the transplanted organs. AMR is one of the most important adverse events after organ transplantation and if untreated, leads to significant graft loss. During AMR, C4d binds covalently to the target structures, which makes it easy to detect with corresponding antibodies. Currently, all renal transplant biopsies and biopsies from other organs as well, are required to stain with C4d antibody.
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UniProt
- P0C0L4
Antigène
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