TRERF1 anticorps (AA 101-200)

N° du produit ABIN872395

Cet anticorps Lapin Polyclonal détecte spécifiquement TRERF1 dans ELISA, IF (cc), IF (p), IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour TRERF1 anticorps (AA 101-200) (ABIN872395)

Antigène: TRERF1 (Transcriptional Regulating Factor 1 (TRERF1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRERF1 est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-TRERF1 anticorps

Épitope: AA 101-200

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TReP132/RAPA

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur TRERF1

Antigène: TRERF1 (Transcriptional Regulating Factor 1 (TRERF1))

Autre désignation: TReP132

Sujet:

Synonyms: BCAR2, Breast cancer anti estrogen resistance 2, Breast cancer anti-estrogen resistance 2, RAPA, rapa 1, rapa 2, rapa1, rapa2, RP1 139D8.5, Transcriptional regulating factor 1, Transcriptional regulating protein 132, Transcriptional-regulating factor 1, Transcriptional-regulating protein 132, TREF1_HUMAN, TReP 132, TREP132, TRERF1, Zinc finger protein rapa, Zinc finger transcription factor TReP 132, Zinc finger transcription factor TReP-132.

Background: Activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.Tissue specificity:Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic HepG2 and HK293 cells.

ID gène: 55809

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding