CEMIP anticorps (AA 101-200)

N° du produit ABIN872432

L’anticorps Lapin Polyclonal anti-CEMIP a été validé pour WB, ELISA, IF (cc), IF (p), IHC (fro) et IHC (p). Il convient pour détecter CEMIP dans des échantillons de Humain, Souris et Rat. Il y a 1 publication disponible.

Aperçu rapide pour CEMIP anticorps (AA 101-200) (ABIN872432)

Antigène: CEMIP (Cell Migration Inducing Hyaluronan Binding Protein (CEMIP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CEMIP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CEMIP anticorps

Épitope: AA 101-200

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TMEM2L

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CEMIP (ABIN872432)

Liang, Fang, Yang, Song: "Silencing of CEMIP suppresses Wnt/β-catenin/Snail signaling transduction and inhibits EMT program of colorectal cancer cells." dans: Acta histochemica, Vol. 120, Issue 1, pp. 56-63, (2017) (PubMed).

Détails sur CEMIP

Antigène: CEMIP (Cell Migration Inducing Hyaluronan Binding Protein (CEMIP))

Autre désignation: CEMIP

Sujet:

Synonyms: CCSP1, TMEM2L, KIAA1199, Cell migration-inducing and hyaluronan-binding protein, CEMIP, HYBID

Background: Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.

ID gène: 57214

UniProt: Q8WUJ3