CEND1 anticorps (AA 4-100)

N° du produit ABIN872436

Cet anticorps anti-CEND1 est un anticorps Lapin Polyclonal détectant CEND1 dans ELISA, WB, IF (cc), IF (p), IHC (fro) et IHC (p). Adapté pour Souris et Rat.

Aperçu rapide pour CEND1 anticorps (AA 4-100) (ABIN872436)

Antigène: CEND1 (Cell Cycle Exit and Neuronal Differentiation 1 (CEND1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CEND1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CEND1 anticorps

Épitope: AA 4-100

Réactivité croisée: Souris, Rat

Homologie: Human,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CEND1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur CEND1

Antigène: CEND1 (Cell Cycle Exit and Neuronal Differentiation 1 (CEND1))

Autre désignation: CEND1

Sujet:

Synonyms: BM88, BM88 antigen, Cell cycle exit and neuronal dferentiation 1, Cell cycle exit and neuronal dferentiation protein 1, FLJ90066, MGC34326, CEND_HUMAN

Background: BM88 is a 149 amino acid protein that belongs to the CEND1 familly. Involved in neuroblastoma cell differentiation, BM88 is a single-pass type IV membrane protein that is neuron specific. It is suggested that BM88 forms a dimer of two identical polypeptides linked by disulfide bridges. BM88 has a central proline-rich region containing four PxxP motifs, which typically bind SRC homology-3 (SH3) domains, as well as a putative C-terminal transmembrane region, and several potential sites for N-glycosylation, myristoylation and phosphorylation. It is also suggested that a novel signaling mechanism exists by which BM88 interferes with calcium release from inositol 1,4,5-trisphosphate-sensitive stores and exerts anti-proliferative and anti-apoptotic functions. BM88 is an important molecular target for HDAC inhibition, and transcription of BM88 is induced by trichostatin-A.

ID gène: 51286