CLASP1 anticorps (AA 30-130)

N° du produit ABIN872439

Cet anticorps anti-CLASP1 est un anticorps Lapin Polyclonal détectant CLASP1 dans WB, ELISA, IHC (p), IF (cc), IF (p) et IHC (fro). Adapté pour Humain.

Aperçu rapide pour CLASP1 anticorps (AA 30-130) (ABIN872439)

Antigène: CLASP1 (Cytoplasmic Linker Associated Protein 1 (CLASP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLASP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-CLASP1 anticorps

Épitope: AA 30-130

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CLASP1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur CLASP1

Antigène: CLASP1 (Cytoplasmic Linker Associated Protein 1 (CLASP1))

Autre désignation: CLASP1

Sujet:

Synonyms: CLAP1_HUMAN, clasp1, CLIP associating protein 1, CLIP associating protein CLASP1, CLIP-associating protein 1, Cytoplasmic linker associated protein 1, Cytoplasmic linker-associated protein 1, hOrbit1, MAST1, Multiple asters 1, Multiple asters homolog 1, Protein Orbit homolog 1.

Background: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

ID gène: 23332

Pathways: Dynamique des Microtubules, M Phase, Maintenance of Protein Location