SRGN anticorps (AA 61-158)

N° du produit ABIN872475

Cet anticorps anti-SRGN est un anticorps Lapin Polyclonal détectant SRGN dans ELISA, IF (cc), IF (p), IHC (fro) et IHC (p). Adapté pour Humain.

Aperçu rapide pour SRGN anticorps (AA 61-158) (ABIN872475)

Antigène: SRGN (serglycin (SRGN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRGN est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SRGN anticorps

Épitope: AA 61-158

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Serglycin/SRGN Polyclonal Antibody

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur SRGN

Antigène: SRGN (serglycin (SRGN))

Autre désignation: SRGN

Sujet:

Synonyms: Chondroitin sulfate proteoglycan core protein, Cytolytic granule proteoglycan core protein, Hematopoetic proteoglycan core protein, Mastocytoma proteoglycan core protein, P.PG, PG19 core protein, Pgsg, Platelet proteoglycan core protein, platelet proteoglycan protein core, PLATELET PROTEOGLYCAN PROTEIN CORE, PPG, PRG, PRG1, PROTEOGLYCAN 1, proteoglycan 1, secretory granule, Proteoglycan 10K core protein, Proteoglycan peptide core protein, PROTEOGLYCAN PROTEIN CORE FOR MAST CELL SECRETORY GRANULE, secretory granule proteoglycan 1, Secretory granule proteoglycan core protein, Serglycin, serglycin proteoglycan, Sgc, Srgn, SRGN_HUMAN.

Background: Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization.

ID gène: 5552

Pathways: Maintenance of Protein Location