FAIM2 anticorps (AA 211-316)

N° du produit ABIN872627

L’anticorps Lapin Polyclonal anti-FAIM2 a été validé pour ELISA, IHC (p), IF (cc), IF (p) et IHC (fro). Il convient pour détecter FAIM2 dans des échantillons de Humain.

Aperçu rapide pour FAIM2 anticorps (AA 211-316) (ABIN872627)

Antigène: FAIM2 (Fas Apoptotic Inhibitory Molecule 2 (FAIM2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAIM2 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-FAIM2 anticorps

Épitope: AA 211-316

Homologie: Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Chicken,Rabbit,Monkey

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FAIM2

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur FAIM2

Antigène: FAIM2 (Fas Apoptotic Inhibitory Molecule 2 (FAIM2))

Autre désignation: FAIM2

Sujet:

Synonyms: FAIM 2, Fas apoptotic inhibitory molecule 2, LFG, Leguard, Neural membrane protein 35, NGP 35, NGP35, NMP 35, NMP35, Protein leguard, TMBIM 2, TMBIM2, Transmembrane BAX inhibitor mot containing 2, Transmembrane BAX inhibitor mot containing protein 2, LFG2_HUMAN.

Background: Programmed cell death regulates a number of biological processes such as normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. FAIM2 is a recently identified protein that can inhibit the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-alpha death signal. In this respect, FAIM2 is functionally similar to the anti-apoptotic proteins FAIM, FLIP and Bcl-xL. FAIM2, a seven membrane spanning protein, can bind the Fas receptor but does not regulate Fas expression or inhibit binding of FADD to Fas. FAIM2 is widely distributed, but highly expressed in the hippocampus and other neural tissues. FAIM2 was also identified as the neural membrane protein 35 (NMP35) and its expression is known to be regulated by the Phosphatidylinositol 3-kinase-Akt/PKB pathway.

ID gène: 23017