HAX1 anticorps (AA 191-279)

N° du produit ABIN872663

L’anticorps Lapin Polyclonal anti-HAX1 a été validé pour WB, ELISA, IF (cc), IF (p), IHC (p) et IHC (fro). Il convient pour détecter HAX1 dans des échantillons de Humain.

Aperçu rapide pour HAX1 anticorps (AA 191-279) (ABIN872663)

Antigène: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HAX1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-HAX1 anticorps

Épitope: AA 191-279

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HAX1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur HAX1

Antigène: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Autre désignation: HAX1

Sujet:

Synonyms: HAX 1, Hax1a, HCLS1 and PKD2 associated protein, HCLS1 associated protein, HCLS1 associated protein X 1, HCLSBP1, HS 1 associated protein X 1, HS 1 binding protein, HS1 associating protein X 1, HS1 binding protein 1, HS1 binding protein, HS1BP1, SCN3.

Background: RelevanceHAX1 associates with HS1, binding to its N-terminal region. It is also known to associate with PKD2 (involved in polycystic kidney disease) and with cortactin/EMS1. HAX1 is also reported to bind to hairpin structures in vimentin and DNA polymerase beta mRNAs, so may play a role in mRNA stability and transport. It may also function in promoting cell survival. Defects in HAX1 are the cause of autosomal recessive severe congenital neutropenia 3 (SCN3) also called Kostmann disease.

ID gène: 10456

Pathways: Regulation of Actin Filament Polymerization