FAM21C anticorps (AA 1201-1318)

N° du produit ABIN872706

Cet anticorps anti-FAM21C est un anticorps Lapin Polyclonal détectant FAM21C dans IF (cc), IF (p), ELISA, IHC (fro) et IHC (p). Adapté pour Rat.

Aperçu rapide pour FAM21C anticorps (AA 1201-1318) (ABIN872706)

Antigène: FAM21C (Family with Sequence Similarity 21, Member C (FAM21C))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM21C est non-conjugé

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-FAM21C anticorps

Épitope: AA 1201-1318

Réactivité croisée: Rat

Homologie: Human,Mouse,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FAM21C

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur FAM21C

Antigène: FAM21C (Family with Sequence Similarity 21, Member C (FAM21C))

Autre désignation: Fam21c

Sujet:

Synonyms: FAM21A, Family with sequence similarity 21 member C, Hypothetical protein LOC253725, KIAA0592, Protein FAM21C, FA21C_HUMAN.

Background: Playing a essential role in the fission of tubules that serve as transport intermediates during endosome sorting, the WASH complex is present at the surface of endosomes and functions to recruit and activate the Arp2/3 complex for induction of actin polymerization. FAM21, Putative WASH complex subunit FAM21, is a component of the WASH complex. Having undergone evolutionary duplication, four highly homologous family members exist including FAM21A, FAM21B, FAM21C and FAM21D. FAM21 links the WASH complex to endosomes and is required for WASM-dependent retromer-mediated sorting. Also, by directly interacting with CapZ, FAM21 inhibits its anti-capping activity, thereby regulating actin dynamics.

ID gène: 253725