FAIM3 anticorps (AA 61-160)

N° du produit ABIN872837

L’anticorps Lapin Polyclonal anti-FAIM3 a été validé pour WB, ELISA, IF (cc), IF (p), IHC (p), ICC et IHC (fro). Il convient pour détecter FAIM3 dans des échantillons de Humain et Souris.

Aperçu rapide pour FAIM3 anticorps (AA 61-160) (ABIN872837)

Antigène: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAIM3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-FAIM3 anticorps

Épitope: AA 61-160

Réactivité croisée: Humain, Souris

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FAIM3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur FAIM3

Antigène: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Autre désignation: FAIM3

Sujet:

Synonyms: Faim3,FAIM3_HUMAN,Fas apoptotic inhibitory molecule 3,Fc mu receptor,R,IgM Fc receptor,Immunoglobulin mu Fc receptor,Regulator of Fas induced apoptosis,Regulator of Fas-induced apoptosis Toso,TOSO.

Background: The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.Tissue specificity: Expressed in lymph nodes, peripheral blood leukocytes, lung, thymus and kidneys. Very weak expression detected in spleen, liver, heart, and salivary gland.