SKA3 anticorps (AA 201-300)

N° du produit ABIN872869

Cet anticorps Lapin Polyclonal détecte spécifiquement SKA3 dans ELISA, WB, IHC (p), IF (cc), IF (p) et IHC (fro). Il présente une réactivité envers Humain et Rat et a été mentionné dans 1 publication.

Aperçu rapide pour SKA3 anticorps (AA 201-300) (ABIN872869)

Antigène: SKA3 (Spindle and Kinetochore Associated Complex Subunit 3 (SKA3))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SKA3 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-SKA3 anticorps

Épitope: AA 201-300

Réactivité croisée: Humain, Rat

Homologie: Mouse,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SKA3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-SKA3 (ABIN872869)

Hou, Wang, Huang, Sun, Zhao, Shi, Li, Wang, He, Tam, Wu: "SKA3 Promotes tumor growth by regulating CDK2/P53 phosphorylation in hepatocellular carcinoma." dans: Cell death & disease, Vol. 10, Issue 12, pp. 929, (2020) (PubMed).

Détails sur SKA3

Antigène: SKA3 (Spindle and Kinetochore Associated Complex Subunit 3 (SKA3))

Autre désignation: SKA3

Sujet:

Synonyms: C13orf3, RAMA1, SKA3, SKA3_HUMAN, Spindle and kinetochore associated complex subunit 3, Spindle and kinetochore-associated protein 3.

Background: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization.