TXNDC5 anticorps (AA 251-350)

N° du produit ABIN872888

L’anticorps Lapin Polyclonal anti-TXNDC5 a été validé pour WB, ELISA, IF (cc), IF (p), IHC (p) et IHC (fro). Il convient pour détecter TXNDC5 dans des échantillons de Humain.

Aperçu rapide pour TXNDC5 anticorps (AA 251-350) (ABIN872888)

Antigène: TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TXNDC5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-TXNDC5 anticorps

Épitope: AA 251-350

Homologie: Human,Mouse,Rat,Dog,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TXNDC5

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur TXNDC5

Antigène: TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))

Autre désignation: TXNDC5

Sujet:

Synonyms: EndoPDI, Endoplasmic reticulum protein ERp46, Endothelial protein disulphide isomerase, ERP46, Hcc 2, PDIA15, Protein disulfide isomerase family A member 15, Thioredoxin domain containing 5 endoplasmic reticulum, thioredoxin domain containing 5, Thioredoxin domain containing protein 5, Thioredoxin like protein p46, Thioredoxin related protein, Thioredoxin-like protein p46, TLP46, TXN5, TXNDC 5, UNQ364, TXND5_HUMAN.

Background: TXNDC5 is a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. ERp19 and ERp46 are two newly discovered ER luminal proteins, related to protein disulphide isomerase. Western and Northern blot analyses have revealed that both ERp19 and ERp46 and their respective mRNAs are highly expressed in the liver as compared with other tissues. Both proteins are enriched in purified liver ER vesicles and were localized specifically to the ER in McA-RH7777 hepatocytes. See Knoblach et al. for details.

ID gène: 81567

Pathways: Cell RedoxHomeostasis