Perilipin A/B anticorps

N° du produit ABIN872948

L’anticorps Lapin Polyclonal anti- a été validé pour WB, FACS, IF (cc), IF (p), ELISA, IHC (fro) et IHC (p). Il convient pour détecter dans des échantillons de Humain et Souris. Il y a 1 publication disponible.

Aperçu rapide pour Perilipin A/B anticorps (ABIN872948)

Antigène: Perilipin A/B

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit

Réactivité croisée: Humain, Souris

Homologie: Dog,Sheep,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Perilipin A+B

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Référence

James, Fox, Afsari, Lee, Clough, Knight, Ashmore, Ashton, Preham, Hoogduijn, Ponzoni, Hancock, Coles, Genever: "Multiparameter Analysis of Human Bone Marrow Stromal Cells Identifies Distinct Immunomodulatory and Differentiation-Competent Subtypes." dans: Stem cell reports, Vol. 4, Issue 6, pp. 1004-15, (2015) (PubMed).

Détail du antigène

Antigène: Perilipin A/B

Autre désignation: Perilipin A+B

Sujet:

Synonyms: Lipid droplet associated protein, PERIA, PERIB, Perilipin A, Perilipin, Perilipin B, PerilipinA, PerilipinB, PLIN.

Background: Perilipin is an intracellular neutral lipid droplet protein that is hormonally regulated. This protein is localized exclusively to the surface of lipid droplets. In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A. Once activated, perilipin has inhibitory affects upon hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body. Perilipin expression is limited to adipocytes and steroidogenic cells. There are currently two known isoforms, Perilipin A and B. Both of these proteins are encoded by a single-copy gene and are the result of differential splicing events.