KIFC1 anticorps
Aperçu rapide pour KIFC1 anticorps (ABIN873143)
Antigène
Voir toutes KIFC1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- KIFC1 Polyclonal Antibody
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Réactivité croisée
- Boeuf (Vache), Humain, Souris, Porc, Rat
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human KIFC1
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Isotype
- IgG
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Indications d'application
- WB(WB=1:500-2000), IHC-P(IHC-P=1:100-500), IHC-F(IHC-F=1:100-500), IF(IF=1:100-500)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C for 12 months.
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Date de péremption
- 12 months
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- KIFC1 (Kinesin Family Member C1 (KIFC1))
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Autre désignation
- KIFC1
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Sujet
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Synonyms: HSET KNSL2, K C1, KC 1, KC1, KC1_HUMAN, Kinesin family member C1, Kinesin like 2, Kinesin like protein 2, Kinesin like protein KC1, Kinesin related protein HSET, Kinesin-like protein 2, Kinesin-like protein KC1, Kinesin-related protein HSET, KNSL 2, KNSL2, Mitotic kinesin like protein 2, MKLP 2,
Background: The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIFC1 is a 673 amino acid protein that belongs to the kinesin-like family of proteins. KIFC1 localizes to the nucleus and contains a C-terminal kinesin-motor domain. Functioning as a minus-end directed microtubule-dependent motor, KIFC1 works together with NuMA and cytoplasmic Dynein to organize microtubule minus ends at spindle poles. HeLa cells deficient in KIFC1 exhibit multipolar mitotic spindles, suggesting that KIFC1 is essential for bipolar spindle formation.
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Poids moléculaire
- 74kDa
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ID gène
- 3833
Antigène
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