Lipin 1 anticorps (AA 501-600)
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- Antigène Voir toutes Lipin 1 (LPIN1) Anticorps
- Lipin 1 (LPIN1)
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Épitope
- AA 501-600
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Lipin 1 est non-conjugé
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Rat
- Homologie
- Human,Mouse,Dog,Cow,Sheep,Pig,Rabbit,Chimpanzee,Goose
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Lipin 1
- Isotype
- IgG
- Top Product
- Discover our top product LPIN1 Anticorps primaire
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anti-Lipin 1 (LPIN1) (AA 729-924) antibody
LPIN1 Reactivité: Rat WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 300-400) antibodyLPIN1 Reactivité: Humain, Rat, Souris WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 741-890) antibodyLPIN1 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 201-300) antibodyLPIN1 Reactivité: Rat, Souris IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 792-890) antibodyLPIN1 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 3D9 unconjugated
anti-Lipin 1 (LPIN1) (AA 218-267) antibodyLPIN1 Reactivité: Humain, Rat, Souris, Chien, Cobaye, Cheval, Lapin, Roussette (Chauve-souris), Hamster, Singe WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 500-600) antibodyLPIN1 Reactivité: Humain, Rat, Souris, Primate WB Hôte: Lapin Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 241-340) antibodyLPIN1 Reactivité: Rat, Souris IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (N-Term) antibodyLPIN1 Reactivité: Humain, Rat, Souris, Chien, Cobaye, Cheval, Lapin, Boeuf (Vache), Porc, Saccharomyces cerevisiae, Mouton, Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- Lipin 1 (LPIN1)
- Autre désignation
- Lipin 1 (LPIN1 Produits)
- Sujet
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Synonyms: KIAA0188, LPIN1, PAP1, Phosphatidate phosphatase LPIN1, LPIN1_HUMAN.
Background: Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 and Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.
- ID gène
- 23175
- Pathways
- Monocarboxylic Acid Catabolic Process
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