HNE anticorps

N° du produit ABIN873270

Cet anticorps anti-HNE est un anticorps Lapin Polyclonal détectant HNE dans WB, ELISA, IF (p), IHC (fro) et IHC (p). Adapté pour . Ce Primary Antibody a été cité dans 13+ publications.

Aperçu rapide pour HNE anticorps (ABIN873270)

Antigène: HNE (4-Hydroxynonenal (HNE))

Reactivité: Veuillez nous consulter SVP

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNE est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-HNE anticorps

Réactivité croisée: Singe, Souris, Rat

Réactivité croisée (Details): 4-Hydroxynonenal

Purification: Purified by Protein A.

Immunogène: 4 Hydroxynonenal conjugated to BSA

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:100-500
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-HNE (ABIN873270)

Shin, Lee, Jang, Kim, Park, Kang, Shim, Ko, Hwang: "Hemolysis-induced hepatic ferroptosis following xenotransfusion of genetically modified pig red blood cells." dans: Scientific reports, Vol. 15, Issue 1, pp. 44014, (2025) (PubMed).

Zhang, Chang, Chen, Beg, Huang, Vick, Wang, Zhang, Yttre, Gupta, Castleberry, Zhang, Dai, Zhu, Song, Yang, Brown, Xu, Ma, Smith, Zielonka, Traylor, Ben Dhaou, Orr, Cui, Chen: "Oxidized LDL stimulates PKM2-mediated mtROS production and phagocytosis." dans: Journal of lipid research, Vol. 66, Issue 5, pp. 100809, (2025) (PubMed).

Târtea, Popa-Wagner, Sfredel, Mitran, Dan, Țucă, Preda, Raicea, Țieranu, Cozma, Vătășescu: "Chitosan Versus Dapagliflozin in a Diabetic Cardiomyopathy Mouse Model." dans: International journal of molecular sciences, Vol. 25, Issue 4, (2024) (PubMed).

Zhang, Chang, Chen, Beg, Huang, Vick, Wang, Zhang, Yttre, Gupta, Castleberry, Zhang, Dai, Song, Zhu, Yang, Brown, Xu, Ma, Smith, Zielonka, Traylor, Dhaou, Orr, Cui, Zheng, Chen: "Oxidized LDL regulates efferocytosis through the CD36-PKM2-mtROS pathway." dans: bioRxiv : the preprint server for biology, (2024) (PubMed).

Chien, Wen, Cheng, Tsai, Chiang, Chien: "Diabetes Upregulates Oxidative Stress and Downregulates Cardiac Protection to Exacerbate Myocardial Ischemia/Reperfusion Injury in Rats." dans: Antioxidants (Basel, Switzerland), Vol. 9, Issue 8, (2020) (PubMed).

Vairappan, Sundhar, Srinivas: "Resveratrol Restores Neuronal Tight Junction Proteins Through Correction of Ammonia and Inflammation in CCl4-Induced Cirrhotic Mice." dans: Molecular neurobiology, Vol. 56, Issue 7, pp. 4718-4729, (2019) (PubMed).

Sapkota, Gaire, Cho, Jeon, Kwon, Jang, Kim, Ryu, Choi: "Eupatilin exerts neuroprotective effects in mice with transient focal cerebral ischemia by reducing microglial activation." dans: PLoS ONE, Vol. 12, Issue 2, pp. e0171479, (2017) (PubMed).

Kagaya, Sasaki, Kino, Taniguchi, Kuraishi, Andoh: "Involvement of oxidative stress in increased peripheral nerve firing during spontaneous dysesthesia in a mouse model of ischemia-reperfusion." dans: Neuroscience letters, Vol. 631, pp. 109-14, (2016) (PubMed).

Zhang, Song, Pang, Zhang, Wan, Yuan, Wu, Liu: "Hydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice." dans: World journal of gastroenterology : WJG, Vol. 21, Issue 14, pp. 4195-209, (2015) (PubMed).

Polverino, Doyle-Eisele, McDonald, Wilder, Royer, Laucho-Contreras, Kelly, Divo, Pinto-Plata, Mauderly, Celli, Tesfaigzi, Owen: "A novel nonhuman primate model of cigarette smoke-induced airway disease." dans: The American journal of pathology, Vol. 185, Issue 3, pp. 741-55, (2015) (PubMed).

Duong, Chami, McMahon, Fong, Dennis, Freedman, Witting: "Pre-treatment with the synthetic antioxidant T-butyl bisphenol protects cerebral tissues from experimental ischemia reperfusion injury." dans: Journal of neurochemistry, Vol. 130, Issue 6, pp. 733-47, (2014) (PubMed).

Haberman, Tickle, Dexheimer, Kim, Tang, Karns, Baldassano, Noe, Rosh, Markowitz, Heyman, Griffiths, Crandall, Mack, Baker, Huttenhower, Keljo, Hyams, Kugathasan, Walters, Aronow, Xavier, Gevers et al.: "Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature. ..." dans: The Journal of clinical investigation, Vol. 124, Issue 8, pp. 3617-33, (2014) (PubMed).

Guo, Tong, Xi, Yang, Dong, Wen: "Neuroprotective effect of calycosin on cerebral ischemia and reperfusion injury in rats." dans: Journal of ethnopharmacology, Vol. 144, Issue 3, pp. 768-74, (2012) (PubMed).

Détails sur HNE

Antigène: HNE (4-Hydroxynonenal (HNE))

Autre désignation: 4 Hydroxynonenal

Classe de substances: Chemical

Sujet:

Synonyms: 4-Hydroxy-2-Nonenal, 4Hydroxynonenal, 4-Hydroxynonenal, 4 HNE, 4HNE, 4-HNE, E-4-Hydroxynonenal-dimethylacetal, 4-HNE-DMA.

Background: Aldehydic products of lipid peroxidation, such as 4 hydroxynonenal (4 HNE), have been implicated in the etiology of pathological changes under oxidative stress as a key mediator of oxidative stress induced cell death. It is a stable product of lipid peroxidation, is proarrhythmic and may contribute to the cytotoxic effects of oxidative stress 4-HNE has been hypothesized to play a key role in cell signal transduction, in a variety of pathways from cell cycle events to cellular adhesion.