CCAR1 anticorps (AA 731-830)
Aperçu rapide pour CCAR1 anticorps (AA 731-830) (ABIN873295)
Antigène
Voir toutes CCAR1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 731-830
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Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human DIS/CCAR1
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Isotype
- IgG
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Indications d'application
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))
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Autre désignation
- CCAR1
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Sujet
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Synonyms: CARP-1, Carp1, CCAR1, CCAR1_HUMAN, Cell cycle and apoptosis regulatory protein 1, cell division cycle and apoptosis regulator 1, Cell division cycle and apoptosis regulator protein 1, Death Inducer with SAP domain, FLJ10590, FLJ10839, FLJ13376, FLJ20734, MGC7730, RP11-437A18.1.
Background: Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation.
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ID gène
- 55749
Antigène
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