Adenylosuccinate Lyase anticorps (AA 185-280) (AbBy Fluor® 350)
Aperçu rapide pour Adenylosuccinate Lyase anticorps (AA 185-280) (AbBy Fluor® 350) (ABIN881599)
Antigène
Voir toutes Adenylosuccinate Lyase (ADSL) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 185-280
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Fonction
- Adenylosuccinate Lyase Antibody, AbBy Fluor-350 Conjugated
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Réactivité croisée
- Humain, Souris, Rat
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Homologie
- Dog,Cow,Pig,Horse
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human Adenylosuccinate Lyase
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Isotype
- IgG
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Indications d'application
- IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- Adenylosuccinate Lyase (ADSL)
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Autre désignation
- Adenylosuccinate Lyase
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Sujet
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Synonyms: Adenylosuccinase, Adenylosuccinate lyase, ADSL, AMPS, ASase, ASL, PUR8_HUMAN.
Background: Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Pathways
- Ribonucleoside Biosynthetic Process
Antigène
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