ANKRD11 anticorps (AA 731-820) (AbBy Fluor® 488)

N° du produit ABIN882687

Cet anticorps anti-ANKRD11 est un anticorps Lapin Polyclonal détectant ANKRD11 dans WB, IF (cc) et IF (p). Adapté pour Humain.

Aperçu rapide pour ANKRD11 anticorps (AA 731-820) (AbBy Fluor® 488) (ABIN882687)

Antigène: ANKRD11 (Ankyrin Repeat Domain 11 (ANKRD11))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANKRD11 est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-ANKRD11 anticorps (AbBy Fluor® 488)

Épitope: AA 731-820

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ANKRD11

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ANKRD11

Antigène: ANKRD11 (Ankyrin Repeat Domain 11 (ANKRD11))

Autre désignation: ANKRD11

Sujet:

Synonyms: ANCO 1, ANCO1, Ankyrin repeat containing cofactor 1, Ankyrin repeat domain 11, Ankyrin repeat domain containing protein 11, LZ16, T13.

Background: Ankyrin is a membrane protein that mediates the attachment of the erythrocyte membrane skeleton to the plasma membrane and interacts with CD44 and inositol triphosphate. It contains three functional domains: a conserved N-terminal ankyrin repeat domain (ARD(consisting of 2224 tandem repeats of 33 amino acids), a spectrin binding domain and a variably sized C-terminal regulatory domain. The ankyrin repeat is a 33-residue motif in proteins consisting of two alpha helices separated by loops. It has been studied using multiple sequence alignment to determine which conserved amino acid residues are critical for folding and stability. Ankyrin-repeat proteins have been associated with a number of human diseases, most notably, the cell cycle inhibitor p16 is associated with cancer and the Notch protein is a key component of cell signaling pathways whose intracellular repeat domain is disrupted in mutations that give rise to the neurological disorder known as CADASIL.

ID gène: 29123