Bax beta anticorps (AA 141-218) (Biotin)
Aperçu rapide pour Bax beta anticorps (AA 141-218) (Biotin) (ABIN884818)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 141-218
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Réactivité croisée
- Humain
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human Bax isoform beta
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Isotype
- IgG
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Indications d'application
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IHC-P 1:200-400
IHC-F 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C for 12 months.
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Date de péremption
- 12 months
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- Bax beta (BAX beta) (BCL2-Associated X Protein (Isoform beta) (BAX beta))
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Sujet
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Synonyms: Apoptosis regulator Bax cytoplasmic isoform beta, BAX, Bax B, Bax beta, BaxB, BCL2 associated X protein, BCL2 associated X protein isoform beta.
Background: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008].
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ID gène
- 581
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UniProt
- Q07812
Antigène
-
