N-Cadherin anticorps (AA 701-800) (AbBy Fluor® 488)

N° du produit ABIN889728

Cet anticorps anti-N-Cadherin est un anticorps Lapin Polyclonal détectant N-Cadherin dans WB, IF (cc) et IF (p). Adapté pour Humain, Souris, Rat, Boeuf (Vache) et Poisson zèbre (Danio rerio).

Aperçu rapide pour N-Cadherin anticorps (AA 701-800) (AbBy Fluor® 488) (ABIN889728)

Antigène: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp N-Cadherin est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-N-Cadherin anticorps (AbBy Fluor® 488)

Épitope: AA 701-800

Réactivité croisée: Boeuf (Vache), Humain, Souris, Rat, Poisson zèbre (Danio rerio)

Homologie: Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human N-cadherin

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur N-Cadherin

Antigène: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Autre désignation: N-cadherin

Sujet:

Synonyms: CDHN, NCAD, CD325, CDw325, Cadherin-2, Neural cadherin, N-cadherin, CDH2, CADH2_HUMAN

Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity).

ID gène: 1000

UniProt: P19022

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane