CIDEC anticorps (AA 101-200) (FITC)

N° du produit ABIN890705

L’anticorps Lapin Polyclonal anti-CIDEC a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter CIDEC dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CIDEC anticorps (AA 101-200) (FITC) (ABIN890705)

Antigène: CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIDEC est conjugé à/à la FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-CIDEC anticorps (FITC)

Épitope: AA 101-200

Specificité: Due to the similarity of this protein with CIDEA in Mouse and Rat, there is a chance that this antibody will react with this protein in those two species based on homology.

Réactivité croisée: Humain, Souris, Rat

Homologie: Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CIDEC

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CIDEC

Antigène: CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))

Autre désignation: CIDEC

Sujet:

Synonyms: CIDE3, FPLD5, FSP27, CIDE-3, Cell death activator CIDE-3, Cell death-inducing DFFA-like effector protein C, Fat-specific protein FSP27 homolog, CIDEC

Background: Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1. May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear. May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression.

ID gène: 63924

UniProt: Q96AQ7