COMMD10 anticorps (AA 91-190) (Biotin)
Aperçu rapide pour COMMD10 anticorps (AA 91-190) (Biotin) (ABIN891786)
Antigène
Voir toutes COMMD10 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 91-190
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Réactivité croisée
- Souris
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Homologie
- Human,Rat,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human COMMD10
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Isotype
- IgG
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Indications d'application
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IHC-P 1:200-400
IHC-F 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C for 12 months.
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Date de péremption
- 12 months
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- COMMD10 (COMM Domain Containing 10 (COMMD10))
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Autre désignation
- COMMD10
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Sujet
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Synonyms: COMM domain containing 10, COMMD 10, FLJ11285, HGNC:30201, HSPC305, PTD002.
Background: COMMD or COMM is a new family of proteins with homology to MURR1, a multifunctional protein that inhibits NFkB. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. The proteins designated as COMMD or COMM domain containing 1-10 are extensively conserved in multicellular eukaryotic organisms and define a novel family of structural and functional homologs of MURR1. The prototype of this family, MURR1/COMMD1, suppresses NFkB not by affecting nuclear translocation or binding of NF-kappaB to cognate motifs, rather, it functions in the nucleus by affecting the association of NF-kappaB with chromatin.
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ID gène
- 51397
Antigène
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