Corin anticorps (AA 165-245) (Biotin)
Aperçu rapide pour Corin anticorps (AA 165-245) (Biotin) (ABIN891975)
Antigène
Voir toutes Corin (CORIN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 165-245
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Réactivité croisée
- Humain, Rat, Mouton
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Homologie
- Mouse,Dog,Pig,Horse
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human Corin
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Isotype
- IgG
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Indications d'application
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IHC-P 1:200-400
IHC-F 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C for 12 months.
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Date de péremption
- 12 months
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- Corin (CORIN) (Corin, Serine Peptidase (CORIN))
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Autre désignation
- Corin
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Sujet
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Synonyms: CRN, ATC2, Lrp4, PEE5, TMPRSS10, Atrial natriuretic peptide-converting enzyme, Corin, Heart-specific serine proteinase ATC2, Pro-ANP-converting enzyme, Transmembrane protease serine 10
Background: Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Isoform 2: has weaker endopeptidase activity compared to isoform 1.
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ID gène
- 10699
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UniProt
- Q9Y5Q5
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Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones
Antigène
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