CSMD2 anticorps (AA 251-350) (Biotin)

N° du produit ABIN892435

Cet anticorps Lapin Polyclonal détecte spécifiquement CSMD2 dans WB, ELISA, IHC (fro) et IHC (p). Il présente une réactivité envers Souris.

Aperçu rapide pour CSMD2 anticorps (AA 251-350) (Biotin) (ABIN892435)

Antigène: CSMD2 (CUB and Sushi Multiple Domains 2 (CSMD2))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CSMD2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CSMD2 anticorps (Biotin)

Épitope: AA 251-350

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CSMD2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur CSMD2

Antigène: CSMD2 (CUB and Sushi Multiple Domains 2 (CSMD2))

Autre désignation: CSMD2

Sujet:

Synonyms: CSMD2, CSMD2_HUMAN, CUB and Sushi SCR repeat domain, CUB and sushi domain-containing protein 2, CUB and sushi multiple domains protein 2, dJ1007G16.1, dJ1007G16.2, dJ947L8.1, KIAA1884.

Background: The CUB and sushi domain-containing proteins, CSMD1-3, are membrane proteins that are involved in cell-cell adhesion and are weakly expressed in most tissues, with higher levels of expression observed in the cerebellum and hippocampus. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas. CSMD2 and CSMD3 are located primarily in the brain and are implicated in some forms of head and neck cancer. Additionally, the CSMD3 gene is a candidate for induction of epileptic seizures.

ID gène: 114784