GIMAP5 anticorps (AA 101-200) (Biotin)

N° du produit ABIN898867

Cet anticorps Lapin Polyclonal détecte spécifiquement GIMAP5 dans WB, ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour GIMAP5 anticorps (AA 101-200) (Biotin) (ABIN898867)

Antigène: GIMAP5 (GTPase, IMAP Family Member 5 (GIMAP5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GIMAP5 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-GIMAP5 anticorps (Biotin)

Épitope: AA 101-200

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GIMAP5

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur GIMAP5

Antigène: GIMAP5 (GTPase, IMAP Family Member 5 (GIMAP5))

Autre désignation: GIMAP5

Sujet:

Synonyms: HIMAP3, IAN4, IAN4L1, IAN5, IMAP3, FLJ11296, GIMAP 5, GTPase IMAP family member 5, GTPase, IMAP family member 5, immunity-associated nucleotide 5, hIAN5, IAN 5, Immune associated nucleotide 4 like 1, Immunity associated nucleotide 4 like 1 protein, Immunity associated protein 3, GIMA5_HUMAN.

Background: GIMAP5, also known as IAN5, IAN4L1 (immunity-associated nucleotide 4-like 1 protein), IAN4, IMAP3, HIMAP3 or IROD, is a 307 amino acid single-pass type IV membrane protein of the mitochondrial outer membrane. A member of the GTP-binding superfamily and the immuno-associated nucleotide (IAN) subfamily, GIMAP5 plays a role in T-cell survival and mitochondrial integrity. GIMAP5 is highly expressed in CD4 and CD8-positive T-cells and monocytes, as well as B-lymphocyte-derived neoplasms. GIMAP5 exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 7q36.1. Defects in the GIMAP5 gene are associated with systemic lupus erythematosus.

ID gène: 55340

UniProt: Q96F15

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response